Comprehensive range of Antibiotics, Antimycotics and Antiviral agents. Whether you require an antibiotic as a cell culture additive to prevent contamination, as a cancer research tool, or a rare antibiotic to study the ever increasing epidemic of antibiotic resistance, we provide a myriad of choices.
Antibiotics are essential in retaining the purity for a particular selection factor in a population of cells. Resistance to a variety of harmful antibiotics that interfere with desirable protein synthesis can be conferred through the use of cell culture products. Astral Scientific has had particular success in the supply of the following antibiotics.
- Hygromycin B is a standard antibiotic that selects for exclusively hygromycin resistant cells.
- Puromycin is an antibiotic that inhibits translation via premature chain termination; it is toxic to both prokaryotic and eukaryotic cells.
- Blasticidin kills both eukaryotic and prokaryotic cells by inhibiting peptide bond formation. Resistance to blasticidin occurs with expression of one of three genes: bsr, bls, or BDS.
G-418 inhibits polypeptide synthesis in prokaryotic and eukaryotic cells and is structurally related to gentamycin.